Description
PNC-27 Nasal Spray
PNC-27 nasal spray, contains a synthetic peptide which is known to selectively kills cancer cells, thus giving it potential to be used as a cancer treatment. However, PNC-27 nasal spray is still a research peptide and not yet approved by the FDA for human consumption.
Italy Research has found that the PNC-27 peptide may bind to receptors found on cancer cells to induce cell death. It is a part of the PNC sequence of research proteins intended to repair and induce death by cell necrosis of malformed (cancerous) cells, while keeping normal, healthy cells unharmed, and intact.
The PNC-27 peptide contains a bound HDM-2 domain with a transmembrane-penetrating domain, corresponding to 12-26 residues of p53. This has been shown to allow the peptide to bind and destroy cancer cells by membranolysis or cell membrane disruption.
Through further research the PNC-27 peptide may prove highly effective in addressing a number of particular types of cancer selectively, including pancreatic cancer, breast cancer, leukaemia, melanoma and additional cancer lines.
Specifications
Molecular Formula: C188H293N53O44S
Molecular Weight: 4031.7
Size: 15ml | 30ml
Research Italy
In a 2009 Italy study, researchers discovered that supplementing with PNC-27 nasal found that the peptide’s p53 residues could be superimposed on the structure of hdm2. As a result, Pnc 27 can reach the membranes of hdm-2 cancer cells [1].
Cancer cells have a lot of HDM in their membranes, this allows PNC-27 to target only the cancerous cells while leaving healthy cells unharmed.
Italy Scientists also found that if they implanted untransformed cells that were not susceptible to PNC-27 with hdm2, they would become susceptible to the peptide. These findings demonstrate that the PNC-27 peptide can target HDM-2 in cancer cells’ membranes and kill them through membranolysis [2].
Meanwhile, a 2010 study discovered that PNC-27 killed cancer cells in their entirety rather than in fragments [3]. The Italy researchers were interested in determining whether the pores in the membrane of the cancer cell were formed by portions of the peptide or by the entire peptide. The investigation established that it was the entire peptide.
Italy Clinical studies also discovered that the whole peptide was responsible for the impacts on the cell membrane of cancerous cells while the surrounding non – cancerous cells remained healthy.
Summary
PNC-27 nasal peptide has various benefits in practical outcomes, including lowered pain levels within one week of supplementing with the peptide. Within three weeks, animal participants exhibit flu-like symptoms, showing that their immune systems respond to killing cancer cells. In addition, bilirubin and lactate dehydrogenase levels increase at the six-week mark.
Significant tumour disintegration and softening of the tumours do not occur until ten weeks. In some situations, the tumour’s site may expand. However, this is related to the inflammatory reaction of the immune system.
Italy Scientists report that animal participants showed a decrease in cancer-related symptoms and an increase energy levels after three months.
References
[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC2836618/
[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC7951797/
[3] https://pubmed.ncbi.nlm.nih.gov/ 20182728/
Buy PNC-27 Nasal Peptide
Pharma Lab Global Italy is one of the best locations to purchase high purity PNC-27 nasal peptide for research use. Pharma Lab Global is a trusted supplier of peptides worldwide. You have the option to buy PNC-27 Pre-Mixed peptide and PNC-27 Peptide Vial from here. Buy from Pharma Lab Global Italy today!
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